MiCardia has developed an array of advanced annuloplasty devices which may be adjusted intra-operatively or post-operatively, dynamically after they are surgically placed in either the mitral valve annulus and/or tricuspid valve annulus position(s).
The technology allows changes to the shape and the size of the annuloplasty ring while viewing the adjustment of geometry in real time using echo (ultrasound), without requiring additional invasive surgery on the mitral or tricuspid valve annulus.
The Dynamic Annuloplasty Platform includes semi-rigid and rigid shapes for the treatment of mitral and tricuspid regurgitation recurrence with various etiologies. Two distinct families of dynamic technology are being developed at MiCardia, both involving a straightforward conventional implantation following a tried-and-tested surgical approach requiring no new maneuvers for the surgeon.
- MiCardia's patented shape-memory nitinol family comprises three configurations of device in five sizes for ischemic and degenerative mitral valve repair, and a tricuspid device also available in five sizes. Various designs under development allow for adjustment immediately after surgery on a beating heart or a point in the future if regurgitation re-occurs, as it does in up to 50% of patients within three years.
- MiCardia's revolutionary externally activated annuloplasty rings are also aimed at bi-ventricular valve management. They can be adjusted in infinite forward and reverse increments intra-operatively, or at any future time involving a completely non-invasive out-patient "tune-up."
The intra-operative method of activation is used "off-pump" for repair optimization or to treat residual regurgitation. The percutaneous method is used post surgery when mitral regurgitation (MR) re-occurs in ischemic mitral regurgitation. The non-invasive activation method is used for mitral regurgitation recurrence.
